Genome Structure, Replication, Recombination And Repair

The stability of our genomes and their ability to exchange information is critical to survival and evolution of all organisms. This exciting area includes studies in prokaryotes and eukaryotes that examine the mechanisms and regulation of DNA replication, the mechanisms of genetic recombination, and the repair of DNA damage caused by mutagenic agents and the environment. Studies on centromere and telomere structure function and role in disease are also conducted in this subgroup. Additionally, the evolution of the genome structure is being studied using experimental and computational approaches.

Program Faculty include: G. Churchward, G. Crouse, S. Devine, P. Doetsch, B. Kelly, I. Matsumura, J. Nickerson, J. Thomas, P. Vertino, S. Warren, S. Yokoyama, W. Zhou, M. Zwick.