Molecular Evolution & Evolutionary Genetics

Experimental Evolution
Molecular evolution, synthetic biology, and the origins of living systems

Recent publications:

• Gao, R.; Lynn, D.G. 2007 "Integration of Rotation and Piston Motions in Coiled-Coil Signal Transduction." /J Bacteriol./ 189: 6048-6056.
• Dong, J; Canfield, JM; Mehta, AK; Stokes, JE; Tian, B; Childers, WS; Simmons, JA; Mao, Z; Scott, RA; Warncke, K; Lynn, DG. 2007 "Engineering metal ion coordination to regulate amyloid fibril assembly and toxicity." /Proc Natl. Acad. Sci. USA/, 104: 13313-13318.
• Keyes, WJ; Palmer, AG; Erbil, WK; Taylor, JV; Apkarian, RP; Weeks, ER; Lynn, DG 2007 "Semagenesis and the Parasitic Angiosperm /Striga asiatica/", /Plant J/., 51: 707-716.
• Hud, N.; Li, X.; Lynn, D.G. 2007 "Addressing the Problems of Base Pairing and Strand Cyclization in Template-Directed Synthesis. A Case for the Utility and Necessity of Molecular Midwives and Reversible Backbone Linkages for the Origin of proto-RNA." /Biodiversity/ 4: 768-83.
• Mehta, AK; Lu, K; Childers, WS; Liang, Y; Dublin, S; Dong, J; Snyder, JP; Skanthakumar, S; Thiyagerajan, P; Lynn, DG. 2008 "Facial Symmetry in Self-assembly", J. Am. Chem. Soc., 130, 9829-9835.
• Lin, Y-H.; Gao, R.; Binns, A.N.; Lynn, D.G. 2008 "Capturing the VirA/VirG TCS of Agrobacterium tumefaciens". Ch 11 in Bacterial Signal Transduction: Network and Drug Targets, Ryutaro Utsumi, Ed. Landes Bioscience and Springer Science, 16 pp.
• Lin, Y-H.; Binns, A.N.; Lynn, D.G. 2008 "The Initial Steps in Agrobacterium tumefaciens Pathogenesis: Chemical Biology of Host Recognition", Ch 6 in Agrobacterium tumefaciens, T. Tzfira and V. Citovsky, Ed., pp 221-241.
• Palmer, A.G.; Liu, Y.; Adkins, S.M.; Zhang, X.; Wu, I-L.; Chen, X.; Lynn, D.G. 2008. "The Molecular Language of Semagenesis". Plant Signaling & Behavior, 3:8, 560-561.
• Liang, Y.; Pingali, S.V.; Jogalekar, A.S.; Snyder, J.P.; Thiyagarajan, P.; Lynn, D.G. 2008. "Cross-strand Pairing and Amyloid Assembly", Biochemistry, 47: 10018-10026.
• Liang, Y.; Gao, P.; Pingali, S.V.; Pabit, S.; Thiyagarajan, P.; Berland, K. M.; Lynn, D.G. 2008." Light Harvesting Antenna on an Amyloid Scaffold". ChemComm. DOI:10.1039.