Drug Development: Searching for Patterns

Immunization is often hailed as one of medicine's greatest triumphs. Yet its success has been largely accomplished without fully understanding exactly how it works. Take, for example, one of humanity's best vaccines -- YF-17D, which protects against yellow fever... It worked, but "nobody really knew why," says Dr. Bali Pulendran, faculty member of Immunology and Molecular Pathogenesis at Emory University in Atlanta, Georgia...Pulendran's analysis of the yellow fever vaccine was widely regarded as proof of concept for the systems biology approach.

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