Chestnut leaves yield extract that disarms deadly staph bacteria
Leaves of the European chestnut tree contain ingredients with the power to disarm dangerous staph bacteria without boosting its drug resistance, scientists have found.
PLOS ONE is publishing the study of a chestnut leaf extract, rich in ursene and oleanene derivatives, that blocks Staphlococcus aureus virulence and pathogenesis without detectable resistance.
The use of chestnut leaves in traditional folk remedies inspired the research, led by Dr. Cassandra Quave, an ethnobotanist at Emory University and a faculty member in the MMG and MSP programs.
The discovery holds potential for new ways to both treat and prevent infections of methicillin-resistant S. aureus, or MRSA, without fueling the growing problem of drug-resistant pathogens.
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