Rescuing existing antibiotics with adjuvants
Gerald Wright from McMaster University, made the case for fighting antibiotic resistance by combining known antibiotics with non-antibiotic drugs that are used to treat other conditions, which he called adjuvants. Emory ethnobotanist and faculty member in the MMG and MSP programs, Cassandra Quave, whose laboratory specializing in looking for anti-bacterial activities in medicinal plants, commented when he proposed that natural products from fungi and plants might be a more rewarding place to look for more anti-bacterial compounds.
Indeed, many of the points he made on strategies to overcome antibiotic resistance could apply to Quave’s approach. She and her colleagues have been investigating compounds that can disrupt biofilms, thus enhancing antibiotic activity.